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diagnosis infections causes endocarditis lifecycle parasite pulmonary brain cardiology management negative abscess bcnie betadglucan concurrent culture galactomannan hivaids infective microbiology
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Endemic fungi ( ... < 200: PCP, Aspergillus ... spp, Endemic fungi ... failure, COPD, Lung ... diagnosis #evaluation #differential
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Negative Abscess - Differential ... : Aspergillus, Cryptococcus ... : Aspergillus, Mucormycosis ... Negative #Abscess #Differential ... #Diagnosis #InfectiousDiseases
Differential diagnosis of Skin + Eye infections • Bacterial: Staph spp, Strep spp, Pseudomonas spp, Bartonella,
Differential diagnosis ... VZV, CMV, HIV • Fungal ... : Candida spp, Aspergillus ... #dermatology #InfectiousDiseases ... Diagnosis #viral #fungal
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... Polysaccharide cell wall component ... of many fungi ... BAL GM does not differentiate ... Clav (may be + as long
Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
difficile (gut) • Fungi ... (mucosa), Aspergillus ... : Aspergillus spp ... Infections #Timeline #differential ... diagnosis #causes #infectiousdiseases
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
Gram-negative bacilli - Fungi ... (Candida, Aspergillus ... Gram-negative bacilli - Fungi ... Pathogens #Diagnosis #Differential ... #InfectiousDiseases
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
• Cell wall component ... of many fungi ... in BAL does not differentiate ... result in + as long ... closely related fungi
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Pericardial Effusion - Differential ... Coxiella burnetii • Fungal ... : Histoplasma, Aspergillus ... - Metastatic: Lung ... Pericardial #Effusion #Differential
Echinococcus Life Cycle 1) Adult in small intestine eggs 2) Embryonated egg in feces 3) Oncosphere hatches; penetrates intestinal
commonly liver and lung ... LifeCycle #diagnosis #pathophysiology ... #infectiousdiseases ... #cdc #parasite
Rigors And Bacteremia - Overview • Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: ... Lipopolysaccharide components ... Double-stranded RNA • Fungi ... Mannan and glucan components ... #InfectiousDiseases
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