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diagnosis differential brain management betadglucan galactomannan pulmonary abscess aids american aspergillus biomarkers cdc comparison falsepositives hiv laboratory mycoses parasite sensitivity
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... ) • Fungi: Aspergillus ... #Infections #Concurrent ... Differential #Diagnosis #causes ... #infectiousdiseases
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... ) • Fungi: Aspergillus ... #Infections #Concurrent ... Differential #Diagnosis #causes ... #infectiousdiseases
Differential Diagnosis for Concurrent Brain and Lung Infections • Bacteria: Strep anginosus, Staph aureus, Klebsiella pneumoniae
Diagnosis for Concurrent ... Brain and Lung ... Toxoplasmosis • Fungi ... #Infections #Concurrent ... Differential #Diagnosis #causes
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Polysaccharide cell wall component ... infection (IFI) ... surfaces - Infections ... decreased with: concurrent ... Clav (may be + as long
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... Abscess Pathophysiology ... Prevotella • Fungal ... #differential #causes
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
• Cell wall component ... of many fungi ... surfaces, Albumin, Infections ... Sensitivity ↓ w/concurrent ... result in + as long
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Pseudomonas FUNGAL ... factor • May cause ... #Infections #HIV ... differential #diagnosis #infectiousdiseases
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Aspergillosis Pathophysiology ... change in the lungs ... nails, bronchi, lungs ... ) #Mycoses #InfectiousDiseases ... #Fungal #Diagnosis
Trypanosomiasis - Trypanosoma cruzi Life Cycle 1) Triatomine bug takes a blood meal (passes metacyclic trypomastigotes in
a blood meal (passes ... amastigotes in new infection ... TrypanosomaCruzi #Tcruzi #LifeCycle ... #diagnosis #pathophysiology ... #infectiousdiseases
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... COMMON CAUSES + ... : Lungs (40-60%) ... negative bacteria, fungi
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