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diagnosis betadglucan cancer colon colorectal fever galactomannan gastroenterology infectiousdiseases rheumatology risk screening stratification table tests abscess antibiotics aspergillus biomarkers causes
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Polysaccharide cell wall component ... infection (IFI) ... surfaces - Infections ... Clav (may be + as long ... Galactomannan #diagnosis #comparison
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
and Management ... polymicrobial infection ... Putrid sputum/sour-tasting ... Diagnosis: • CBC ... Prevotella • Fungal
“Step by Step” – the new kid on the block – aims to risk stratify this
serious bacterial infections ... for each of the components ... of the algorithm ... <10,000/mm3 - CRP ... #Diagnosis #Management
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Galactomannan Testing ... • Cell wall component ... surfaces, Albumin, Infections ... result in + as long ... #Testing #FalsePositives
Performance Characteristics for Colorectal Cancer Screening Tests Stool/blood-based tests: • FIT: 79% sensitivity, 94% specificity for CRC
, Long term reduction ... , Long term reduction ... Screening #Tests #comparison ... #table #management ... #Testing
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Diagnosis: • Direct fungal ... Urinary antigen testing ... change in the lungs ... nails, bronchi, lungs ... #Diagnosis #Management
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
Key Components: ... Skin exam for infection ... event, follow ACC algorithm ... unless prior heart/lung ... medical and surgical management
ACA Colorectal Cancer Screening Guidelines When to Screen? When to Stop? Family History Performance Characteristics for Colorectal Cancer Screening Tests Stool/blood-based
, Long term reduction ... , Long term reduction ... Indications #Tests #comparison ... #table #management ... #Testing #Indications
Fluid Responsiveness and Fluid Tolerance Testing - OnePager Summary Fluid resuscitation can be beneficial when required or
Fluid Tolerance Testing ... via cold saline injection ... Responsiveness #Tolerance #testing ... #criticalcare #comparison ... #challenges #management
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
: Lungs (40-60%) ... negative bacteria, fungi ... leukopenia, increased Cr ... INITIAL MANAGEMENT ... ADVANCED MANAGEMENT
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