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diagnosis causes infections betadglucan galactomannan infectiousdiseases pulmonary biomarkers brain concurrent eosinophilia microbiology table aids algorithm allergy cardiology cd4 diseases effusion
Fungal Biomarkers: Comparing Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi •
Fungal Biomarkers ... Polysaccharide cell wall component ... of many fungi ... febrilepodcast #Fungal ... Galactomannan #diagnosis #comparison
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
Important Fungal ... and chitin in fungal ... exceptions are Aspergillus ... polysaccharide component ... #fungus #comparison
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... Polysaccharide cell wall component ... BAL GM does not differentiate ... Clav (may be + as long ... Galactomannan #diagnosis #comparison
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
• Cell wall component ... of many fungi ... in BAL does not differentiate ... result in + as long ... closely related fungi
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Pericardial Effusion - Differential ... Coxiella burnetii • Fungal ... : Histoplasma, Aspergillus ... - Metastatic: Lung ... Pericardial #Effusion #Differential
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
> 200: Endemic fungi ... CD4 < 200: PCP, Aspergillus ... spp, Endemic fungi ... failure, COPD, Lung ... diagnosis #evaluation #differential
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
Eosinophilia - Differential ... GI, lung, skin), ... ascariasis), Scabies, Fungi ... (Cocci, Aspergillus ... #Eosinophilia #Differential
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
to Eosinophilic Lung ... Infectious (Variable) - Fungal ... #Eosinophilic #Lung ... Diseases #pulmonary #differential ... #diagnosis #comparison
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
- Influenza A FUNGAL ... - Aspergillus ... - small cell lung ... Rhombencephalitis #Differential
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... Pseudomonas FUNGAL ... since cART) Aspergillus ... AIDS #pulmonary #differential
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