11 results
An Approach to Jaundice Workup Algorithm by CBC and LFT Pattern

- Dr. Eric Strong @DrEricStrong

#Jaundice #Workup
Approach to Jaundice Workup ... Algorithm by CBC ... and LFT Pattern ... LFTs #Diagnosis #Hepatology ... #Differential
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... : - SSc, PBC/ ... Antinuclear #Antibody #Testing ... #differential # ... diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... decreased PLT count: CBC ... smear, HIV/HCV testing ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... hypertension • Unusual RBC ... Hemolytic #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody Testing ... : • SSc, PBC/SSc ... Antinuclear #Antibody #Testing ... #differential # ... diagnosis #rheumatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... Proximal limb muscle wasting ... bile ducts Differential ... cholangitis #diagnosis #workup ... #hepatology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... especially in the setting ... #Bandemia #differential ... #CBC #hematology ... #pathophysiology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody Testing ... Cytoplasmic Patterns ... #Cytoplasmic #Patterns ... #differential # ... diagnosis #rheumatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
evaluation of the pattern ... decision for repeat testing ... body mass index; FBC ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... , erythema and WBC ... • Is there a pattern ... an asymmetric pattern ... #Joint #pain #Differential