64 results
Primary Bone Tumors - Differential Diagnosis Algorithm 

Metastatic - Most common tumour in adults
 - Breast
Primary Bone Tumors ... Differential Diagnosis Algorithm ... Tumours #MSK #Differential ... #Diagnosis #Algorithm ... #Orthopedics #Causes
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long bones ... • XR, MRI to ... differential #diagnosis #causes ... #hematology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic Algorithm ... and Causes Increased ... hyperplasia of bone ... #Differential #Causes ... #Workup #Hematology
Bone Lesion on X-Ray - Differential Diagnosis Algorithm 
Exostotic
 • Osteochondroma
Asymptomatic &/or Non-Active Bone Scam
 •
Bone Lesion on X-Ray ... Differential Diagnosis Algorithm ... BoneLesion #XRay #MSK ... Differential #Diagnosis #Algorithm ... #Orthopedics #Causes
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
Osgood-Schlatter Disease - MSK ... fragmentation and mild bone ... • MRI is more sensitive ... marrow edema and bony ... patella #clinical #mri
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
g/dl LLN B - Bony ... more: • Clonal bone ... focal lesions on MRI ... Causes of false- ... MGUS #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... effect following treatment ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... • Bone marrow ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Differential Diagnosis Algorithm ... Tumours - See Bone ... Gastrointestinal Disease • Bone ... Fractures #Pathologic #MSK ... #Orthopedics #Causes
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... Rule out other causes ... - MRI: inflammation ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology