27 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Proximal tubule Bartter ... loop of Henle Gitelman ... #Nephron #Defects ... #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... delivery to distal nephron ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... loop and distal component ... of Nephron: CHF ... absorption in distal nephron ... KidneyDisease #nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Hypochloremia - Differential ... - Diuresis - Bartter ... - Gitelman ... Cl⁻ with other components ... Diagnosis #Algorithm #Pathophysiology
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Hypomagnesemia - Differential ... Hypomagnesemia - Familial: Bartter ... syndrome and Gitelman ... Hypomagnesemia #differential ... diagnosis #causes #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... thiazide diuretics, Bartter ... syndrome, Gitelman ... #Hypokalemia #Differential ... potassium #low #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Metabolic Alkalosis - Differential ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Metabolic Alkalosis - Differential ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #Nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
ratio 0.5%) Differential ... Refeeding syndrome • Bartter ... syndrome • Pseudo Bartter-Gitelman ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
acid transporter Bartter ... ascending limb Gitelman ... Defects #Kidney #Nephrology ... #Diagnosis #Differential