10 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... Most common symptoms ... disease - Bone symptoms ... Differential #Diagnosis #Algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
with alkaline phosphatase ... increase in alkaline phosphate ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
ALT, Alkaline Phosphatase ... liver Alkaline phosphatase ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology ... #Diagnosis #LFTs
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... Is Low Alkaline Phosphatase ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Hyophosphatasia #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... or symptoms of ... gastroenterology #algorithm ... gastroenterology #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... suspicious clinical symptoms ... ALP, alkaline phosphatase ... #LFTs #Abnormal ... #Algorithm #Hepatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... pattern of spread, B symptoms ... Classification #pathophysiology ... #Hematology #Diagnosis ... #differential #algorithm
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... : • Alkaline phosphatase ... diagnosis #workup #hepatology
Rickets and Osteomalacia: Pathogenesis and Clinical Findings
 • Calcification inhibitors (excess exposure to A1, Fluoride, etidronate)
of bone mineral components ... Phosphate: renal ... disorders, vit D or Phosphate ... #Osteomalacia #pathophysiology ... diagnosis #signs #symptoms
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
thrombocytopenia syndrome (SFTS ... cell lymphoma Pathophysiology ... and the systemic symptoms ... Elevated alkaline phosphatase