9 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... twitter.com/AmyChung #AntiCoagulation ... #Cascade #Anticoagulants ... #Pharmacology #Pathophysiology ... Mechanisms #DOAC #Hematology
Venous Thromboembolism Treatment Algorithm
Branch points: 
Active bleeding?  Active malignancy? Provoked?

- Dr. Joseph Shatzel
@Clotmaster

#Management #VTE #DVT
Venous Thromboembolism ... Treatment Algorithm ... #Venous #Thromboembolism ... #Treatment #Hematology ... #Anticoagulation
Algorithm for the Long-Term Treatment of Venous Thromboembolism 

Reference: https://doi.org/10.1182/blood.2019002364

by Dr. Clive Kearon and Dr. Susan
Algorithm for the ... Treatment of Venous Thromboembolism ... Treatment #Venous #Thromboembolism ... #VTE #Anticoagulation ... #Algorithm #Hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation cascade ... diagnosis #models #hematology ... #pathophysiology ... #anticoagulation ... Rivaroxaban #Edoxaban #heparin
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
stratification algorithm ... molecular weight heparin ... ; VTE = venous thromboembolism ... #Anticoagulation ... #Management #Hematology
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Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... dysfunction (25%) • Hepatic ... Shock (14%) • Thromboembolism ... 100mg/dL) - Heparin ... treatment #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Malignancy - Previous thromboembolism ... Hyperhomocysteinemia - Heparin-induced ... Venous #Arterial #pathophysiology ... #hematology #differential
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... Suggested treatment algorithm ... low-molecular-weight heparin ... #Anticoagulation ... #Management #Hematology
Longterm Venous Thromboembolism Treatment Algorithm
Treat for 3 months and reassess
 • Isolated distal DVT (without cancer)
Longterm Venous Thromboembolism ... Treatment Algorithm ... #Treatment #Algorithm ... #management #hematology ... #anticoagulation