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Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
Diagnosis and workup ... Alzheimer - 1st cause ... Aphaso-apraxo-agnosia syndrome ... - 25% genetic component ... Dementia - 2nd cause
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
- Gitelman syndrome ... - Hungry bones syndrome ... Low #Magnesium #Table ... Classification #Causes ... #Workup #hypomg
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... for secondary causes ... eosinophilia (common causes ... glucocorticoid treatment
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Treatment depends ... maintained fever CAUSES ... • Serotonin syndrome ... #Differential #Causes ... Diagnosis #Management #Workup
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
Causes of Secondary ... • Cushing’s syndrome ... Mineralocorticoid excess syndromes ... #Screening #Workup ... #table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
TTP/HUS, HELLP Syndrome ... Pregnancy (AFLP) Three syndromes ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... with previously stable ... White-coat syndrome ... Guillain-Barre Syndrome ... #Hypertension #Workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... skin that are caused ... Workup: • Complete ... #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
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