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diagnosis differential hematology neurology algorithm cardiology causes anemia summary endocarditis endocrinology erythematosus gravis hemolytic hypocalcemia infectiousdiseases lowcalcium lupus myasthenia pediatrics
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... thrombocythemia), Autoimmune ... disease • vWF ... #treatment #hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
common in SLE, autoimmune ... microsomal) - Autoimmune ... - Vasculitis, e.g ... - Vasculitis, e.g ... diagnosis #table #rheumatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
of Factor IX Acquired ... Malabsorption (e.g ... . celiac disease ... warfarin, DOACs (e.g ... disorders (e.g.
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Hemoglobinopathies (e.g ... Membrane defects (e.g
Causes of Fat Malabsorption - Differential Diagnosis Biliary Duct Obstruction • Autoimmune— PBC, PSC • Infection— liver
Obstruction • Autoimmune ... Cholestatic drugs- e.g ... Insufficiency - Acquired ... Shwachman-Diamond syndrome ... • Short bowel syndrome
Hypocalcemia - Differential Diagnosis Algorithm - Low and High PTH LOW PTH - Hypoparathyroid - Congenital (Pediatric)
• DiGeorge - Acquired ... • Autoimmune ... Vit-D degradation (eg ... hyperphosphatemia (eg ... Tumor lysis syndrome
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
mild to severe, Colour ... (e.g. oculomotor ... (AQP4-lgG disease ... ; e.g. narcolepsy ... Myositis, Comorbid autoimmune
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate LOW PHOSPHATE - Low/NormaI PTH
D Deficiency (e.g ... Phenytoin, Nephrotic Syndrome ... Hepatobiliary Disease ... Hypoparathyroidism (e.g ... Acquired, Autoimmune
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Severe Disease → Remission
) - Vasculitis Management ... • Non-Severe Disease ... immunosuppressive agent (e.g ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
the secondary or acquired ... (eg, systemic juvenile ... • Infection (eg ... Treatment: • Corticosteroids ... #Diagnosis #Management
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