8 results
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic ... Anemia (AIHA) Pathophysiology ... or negative - Smear ... AIHA #Autoimmune #Hemolytic ... #Anemia #Pathophysiology
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
metaplasia, pernicious anemia ... thalassemia, and some hemolytic ... anemias. ... #Clinical #Path ... BloodSmear #Blood #Smear
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... anemia • Cold ... • Compensated hemolysis ... intravascular hemolysis ... agglutinin #disease #hemolytic
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Autoimmune: Warm AIHA, Cold ... Defects: Sickle cell anemia ... Peripheral Blood Smear ... Urobilinogen #Hemolysis
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
to be seen in hemolytic ... microangiopathic hemolytic ... intravascular coagulation, hemolytic ... #Clinical #Path ... BloodSmear #Blood #Smear
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
associated with hemolytic ... anemias, especially ... #Clinical #Path ... BloodSmear #Blood #Smear
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
This smear was from ... spherocytosis and hemolytic ... anemias. ... #Clinical #Path ... BloodSmear #Blood #Smear
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
peripheral blood smears ... can be found in hemolytic ... anemia. pernicious ... #Clinical #Path ... BloodSmear #Blood #Smear