9 results
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... Diagnosis Algorithm ... - Diabetes Insipidus ... Workup Step ... #Sodium #nephrology
Polyuria - Differential Diagnosis Algorithm
Urine Output > 3L /day
Water Diuresis (Urine Osm <100 mOsm/kg)
 • Primary
Polyuria - Differential ... Diagnosis Algorithm ... Diabetes Insipidus ... #Differential # ... #causes #nephrology
Causes of Polyuria - Differential Diagnosis Algorithm
Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min)
Osmotic
- Differential ... Diagnosis Algorithm ... Insipidus - DDAVP ... Insipidus #Polyuria ... #Nephrology #Differential
Polyuria - Differential Diagnosis Algorithm
Polyuria = >3L Urine output / 24 hours
Urine osmolality = 2 (Na
Polyuria - Differential ... Diagnosis Algorithm ... 100 mosm/kg • Diabetes ... Insipidus • Primary ... #nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
water loss, Serum Sodium ... diuresis (see Polyuria ... 300 mmol/kg • Diabetes ... Insipidus Hypodipsia ... Hypernatremia #Nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Diagnosis Workup ... • Euvolemic: Diabetes ... insipidus (central ... #Algorithm #nephrology ... #sodium
Diabetes Insipidus - Diagnosis Algorithm
Tests:
 • Osmolality, Urine AND/OR
 • Osmolality, Serum or Plasma AND
 •
Diabetes Insipidus ... - Diagnosis Algorithm ... Plasma AND • Sodium ... #Algorithm #nephrology ... #differential
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
ATPase Nephrogenic diabetes ... insipidus - Vasopressin ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Primary Polydipsia
Definition: Excessive volitional water intake
Epidemiology:
 • 6-20% of patients with psychiatric disorders - Most commonly
insipidus Differential ... Diagnosis: Diabetes ... intoxication Initial Workup ... , Urine Sodium ... diagnosis #management #nephrology