20 results
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... malignancies Treatments ... with Ca only if EKG ... #Lysis #Syndrome ... TLS #oncology #management
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
BRASH Syndrome ... Typical ECG ... ) BRASH Treatment ... • Aggressive treatment ... #diagnosis #management
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Dysplasias • (e.g ... • Turner Syndrome ... Panhypopituitarism Treatment ... Nervosa • CNS Tumors ... (e.g.
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... hydration - Hyperkalemia ... treatment (no calcium ... unless worrisome EKG ... TLS #diagnosis #management
Hyperkalemia Management
Pseudohyperkalemia: 1. Hemolyzed sample 2. Blood drawn from a site/line where potassium or TPN is
Hyperkalemia Management ... a STAT EKG to assess ... stabilize heart if EKG ... @AnnKumfer #Hyperkalemia ... #Management #treatment
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm
Drugs that prolong QT interval:
 • Class 1a (quinidine,
Torsades de Pointes - Management ... Congenital long QT Syndrome ... Hypomagnesemia • Hypokalemia ... Hypocalcemia (rarely) Treatment ... TorsadesdePointes #TDP #Management
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Budd Chiari syndrome ... disease Imaging and Treatment ... Hypercalcemia 4 ... Recombinant cytokines (e.g ... kinase inhibitors (e.g
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cushing's Syndrome ... exposed tothe sun (e.g ... Cataracts Labs: Hypokalemia ... gluconeogenesis enzymes (e.g ... • The adrenal cortex
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
with: - Thymic tumors ... thyroid, Sjogren syndrome ... “dropping head syndrome ... Serologic and EMG ... Gravis #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
cardiomyopathy, Horner ... Electrodiagnostic studies - EMG ... Treatment: • Plasmapheresis ... #diagnosis #management ... #treatment #neurology