16 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Wilson's disease, Copper ... Extravascular #Causes ... #differential # ... diagnosis #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... type ± C3d • Blood ... smear: Differential ... 2) LOOK FOR a cause ... Anemia #diagnosis #management
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... agents ex. lead, copper ... #Anemia #Differential ... classification #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Deficiency Anemia - Differential ... TSAT, sTfR • Blood ... extravascular) hemolysis ... or deficiency, Copper ... Algorithm #ferritin #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... of Peripheral blood ... WBC count and differential ... hematuria (without casts ... Diagnosis #Workup #Hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... more likely to cause ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... more likely to cause ... Transfusions #diagnosis #management ... #hematology #reactions
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Approach to the differential ... glomerulonephritis; HUS = hemolytic-uremic ... content [85].2>5 red blood ... are listed in order ... Nephrocalcinosis causes
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
pressure as a cause ... perfusion, recheck blood ... adult, 10 ml.kg-1 paediatric ... #Hypotension #Differential ... Checklist #Diagnosis #Management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and autoimmune hemolytic ... the low levels ORDER ... and M panel Management ... DDX - Other causes ... #diagnosis #management