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hematology oncology differential leukemia management lymphoma algorithm causes classification lymphocytic rheumatology workup adult atll clinical common comparison cvid diffuse disorders
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Hodgkin's Lymphoma ... Hodgkin's Lymphoma ... typically of B-cell ... cells, natural ... killer (NK) cells
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... lymphoma SLL ... cells can infiltrate ... smear: Smudge cells ... or basket cells
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... cells and Reed-Sternberg ... cells. ... • The tumor cells ... #lymphoma #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Rapidly rising blast cells ... : Granulocytic cells ... organs When Cancer Cells ... mosquito bites CLL ... #Diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... Lymphocyte - 5% RS cells ... (LP) tumour B cells ... common - T Cell ... ~10% - B-Cell
Adult T-cell Leukemia / Lymphoma (ATLL) - Mimicking Angioimmunoblastic T-cell lymphoma with Hodgkin like cells Features ATLL:
Adult T-cell Leukemia ... Angioimmunoblastic T-cell ... lymphoma with Hodgkin ... like cells Features ... more common T-cell
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
causes: - B or T cell ... lymphomas, Hodgkin ... CD3-CD4+ T cells ... HIV, HTLVI) - Chronic ... #Differential #Diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Age > 50 • Chronic ... Cells on Biopsy ... • Hodgkin's ... Lymphoma #Diffuse
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... lymphocytes, smudge cells ... Transformation to large cell ... lymphoma (Richter ... uw_IMresidency #CLL
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
low red blood cell ... Marrow Failure • Chronic ... treatments • Copper ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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