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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE #hematology ... #rheumatology #
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Care TRICC - NEJM ... - ICU FOCUS - NEJM ... Villaneueva - NEJM ... UGIB TRISS - NEJM ... Transfusion #Thresholds #Hematology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Anti-phospholipid) M Malar Rash ... D Discoid Rash ... erythematosus #rheumatology
Excoriated papules with honey-colored crusting were present on the abdomen, back (Panel A), arms, and legs.
Scabies #Microscopy #Rash ... #NEJM
Crusted Scabies - Physical examination now revealed a generalized erythematous and scaly rash with intense hyperkeratotic
erythematous and scaly rash ... Scabies #Microscopy #NEJM
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... including heliotrope rash ... Myositis #diagnosis #rheumatology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Non-infectious (malignancy, rheumatologic ... causes #Platelets #hematology
Herpes Zoster Mandibularis - The lesions were scattered along the area that is innervated by the
#Mandibularis #Rash ... #NEJM #Shingles
Strongyloides stercoralis Hyperinfection - Physical examination revealed reticulated purpuric patches with dusky centers on the abdomen,
biopsy of the rash ... InfectiousDisease #Rash ... FilariformLarvae #Microscopy #NEJM
Goal-Directed Therapy - Evidence Summary of Major Clinical Trials

 - EGDT: NEJM 2001

 - ProCESS: NEJM
Trials - EGDT: NEJM ... - ProCESS: NEJM ... 2014 - ARISE: NEJM ... - ProMlSe: NEJM