12 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... #Diagnosis #Management ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... (SLE) Clinical ... permeability Diagnosis ... CNS #neurology #rheumatology ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
A subset of hemophagocytic ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... : Overwhelming clinical ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... accumulation of clinical ... Assessment • Clinical ... #management #treatment ... #summary #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Differential Diaqnoses ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
narrowing) • Ultrasound ... Diagnosis: CLINICAL ... DIAGNOSIS based ... exam and imaging Treatment ... #management #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology ... #diagnosis #management
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
importantly, bedside ultrasound ... with presence of pulmonary ... & Dry) is the treatment ... #algorithm #management ... heartfailure #chf #criticalcare
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Relapsing-remitting course +++ Clinical ... filling +++ (risk of pulmonary ... leak #syndrome #diagnosis ... #management #timeline ... #treatment #rheumatology