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differential algorithm dermatology management nutrition secondary systemic thrombocytosis alopecia b12 classification cobalamin elevatedmcv erythematosus fatigue gangrenosum gastronintestinal lowergibleed lupus macrocytosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... Inflammatory: • IBD ... malignancy • Iron ... deficiency anemia
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Inflammation: IBD ... #Deficiency #Causes ... #differential #diagnosis ... #anemia #nutrition
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... - Differential Diagnosis ... Volume (<80 fL) • Iron ... Chronic Disease (e.g ... #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... - Differential Diagnosis ... Deficiency (Eg ... #Differential #Diagnosis ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... • Secondary (e.g ... • Early Iron ... Deficiency # ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... (specifically: iron ... deficiency, hemolysis ... #Causes #hematology
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
fatigue despite clinical ... Crohn's > UC Anemia ... restricted diet/deficiency ... /other causes • ... #Algorithm #diagnosis
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Spoon-shaped • Iron ... deficiency anemia ... halt nail growth (e.g ... #Differential #Diagnosis ... #Algorithm #causes
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... • Common Causes ... intrinsic factor, IF) Clinical ... diarrhea related to IBD ... #diagnosis #management
Occult and Lower Gastronintestinal Bleed - Differential Diagnosis Algorithm Occult (Stool + Occult blood and/or iron deficiency
Occult blood and/or iron ... deficiency anemia ... , asymptomatic IBD ... bowel source (e.g ... #Algorithm #Causes
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