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hematology cascade models anticoagulation apixaban arterial causes clot comparison dabigatran deficiencies deficiency dic differential disseminated edoxaban embolism inhibitor intravascular management
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Summary of Coagulation ... celiac disease, CF, IBD ... ) • Anticoagulant ... Medications - Heparin ... table #comparison #diagnosis
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
at the site of injury ... clot #PT #PTT #diagnosis ... #pathophysiology ... anticoagulation #anticoagulant ... Rivaroxaban #Edoxaban #heparin
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Reduction of pro/anticoagulants ... 100mg/dL) - Heparin ... #diagnosis #causes ... treatment #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Ischemic Liver, IBD ... Hyperhomocysteinemia - Heparin-induced ... intravascular coagulation ... Vasculitis • Injury ... Venous #Arterial #pathophysiology
Review of the Coagulation Cascade Traditional Model: • Parallel extrinsic and intrinsic pathways. Contemporary Model: • 4 key
due to vascular injury ... fibrin, which is cross-linked ... #Cascade #diagnosis ... #models #hematology ... #pathophysiology
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