9 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... symptomatology Differential ... Investigations • Labs: CBC ... Renal #Syndrome #differential ... #diagnosis #nephrology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Pathophysiology: ... commonly renal and pulmonary ... #Diagnosis #Dermatology ... Palpable #Algorithm #Differential
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... With associated pulmonary ... Glomerulonephritis #Vasculitis #differential ... diagnosis #algorithm #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... initiation • Differential ... diagnosis #management #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... #Bandemia #differential ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... Diagnosis: • CBC ... Lung Abscess Differential ... Lung #Abscess #pulmonary ... #differential #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... progressing GN • New pulmonary ... ear disease Differential ... Lab Tests: • CBC ... #diagnosis #rheumatology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Illnesses: • Pulmonary ... complicate MAC pulmonary ... Advanced HIV (CD4 ... Hematologic malignancy ... NTM #Infections #differential
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
or triggers) is crucial ... Pathophysiology ... of NK cells and CD8 ... Diagnosis #Management #Hematology