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diagnosis differential rheumatology lupus erythematosus criteria disorders hematology management pathophysiology table vasculitis acidosis causes clinical clinicopathology comparison cord cryoglobulinemia cryoglobulins
Systemic Lupus Erythematosus (SLE): Pathogenesis • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
(SLE): Pathogenesis ... HLA-DR3 genes, complement ... self-antigens, activating complement ... cytokines such as ... Erythematosus #SLE
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... anticoagulant • Complement ... #Criteria #SLE ... #Systemic #Lupus
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs ... 90% - Low complement ... months to years) Systemic ... 80% - Low complement ... management of SLE
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... antibody positivity, as ... anticoagulant - Low complement ... #Rheumatology #SLE
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... Skin Disease Classification ... RNP antibodies, Complement ... #Systemic #Lupus
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... diseases: - 10% SLE ... • Low serum C4 complement ... erythematosus (SLE ... diagnosis #types #classification
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
infections include systemic ... and amyloidosis as ... well as medications ... See below for table ... helpful paper complements
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
central nervous system ... systemic lupus ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... site in lymphatic system ... with lymphatic system ... B symptoms not as ... Lymphoproliferative #Disorders #Classification
Ellis system of classification system for a tooth fracture: Ellis 1: injury of the crown into enamel
Ellis system of ... classification system ... : tender, may see ... dentin appears as ... Fractures #Ellis #Classification
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