11 results
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
Selected Diseases on Complement ... • SLE C3 ↓ C4 ... ↓ C4 ↓↓ • Cryo ... • Infection eg SBE ... ThePeanutKidney #Complement
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... anticoagulant - Low complement ... (C3, C4, or CH50 ... #Rheumatology #SLE
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
anticoagulant • Complement ... proteins domain: Low C3 ... or low C4, Low C3 ... Classification #Criteria #SLE
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... 90% - Low complement ... Erythematosus (SLE ... 80% - Low complement ... #comparison #table
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
activation • Complement ... Ags tagged with C3 ... complement fragment ... classical pathway (see ... Complement Activation
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... RNP antibodies, Complement ... levels (C3 and ... : Drug induced SLE ... disease activity • C3
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
Metabolism A table ... See IEM schema for ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... Peds #Pediatrics #Table
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
See the lab values ... table for supplemental ... Pathophysiology #Diagnosis #Algorithm ... Peds #Pediatrics #Table
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
See below for table ... helpful paper complements ... #Differential #Table
CA-Bridge Buprenorphine Hospital Quick Start Algorithm - Management of acute opiate withdrawal 
 - Any prescriber
Hospital Quick Start Algorithm ... If patient is stable ... tab sublingual (SL ... - Bup SL onset ... Buprenorphine #Treatment #Algorithm