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diagnosis differential causes brain infections infectiousdiseases management cardiology endocarditis fungal pulmonary aspergillus betadglucan biomarkers candida candidemia cns comparison fungemia galactomannan
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Abscess Etiology ... Lung abscess ... Lung Abscess - Clinical ... Dermatitidis - Cryptococcus
Differential Diagnosis for Concurrent Brain and Lung Infections • Bacteria: Strep anginosus, Staph aureus, Klebsiella pneumoniae
Diagnosis for Concurrent ... Brain and Lung ... Mucormycosis, Cryptococcus ... ID_fellows #Brain #Lung ... #Infections #Concurrent
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... Mucormycosis, Cryptococcus ... febrilepodcast #Brain #Lung ... #Infections #Concurrent
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... Mucormycosis, Cryptococcus ... febrilepodcast #Brain #Lung ... #Infections #Concurrent
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
lesions • 80% with lung ... histoplasmosis, cryptococcus ... Syphilis • Pyogenic Abscess
Lung Nodule - Differential Diagnosis Algorithm Nodule on > 2 Years Without a Change in Size: •
Lung Nodule - Differential ... Diagnosis Algorithm ... Granuloma • Abscess ... polyangiitis (GPA) / microscopic ... Differential #Diagnosis #Algorithm
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
- Negative: Cryptococcus ... Paecilomyces, Cryptococcus ... decreased with: concurrent ... Clav (may be + as long
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
verrucous) • Lung ... Aspergillus • Cryptococcus ... suggests perivalvular abscess ... annular or aortic abscess ... Complications: Abscess
Invasive Fungal Infection (IFI) Invasive fungal infections are severe infections in which fungal pathogens invade normally sterile
pulmonary infections) Cryptococcus ... Diagnosis Culture and microscopy ... galactomannan, cryptococcal ... or drainage of abscesses
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Fluconazole CRYPTOCOCCUS ... level, presence of cryptococcal ... CSF and serum Cryptococcal ... Sinusitis • Brain abscess ... change in the lungs
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