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IDSA Treatment Recommendations for Cryptococcal Meningoencephalitis - Induction, Consolidation and Maintenance Therapy

Table 2. Antifungal Treatment Recommendations
Recommendations for Cryptococcal ... Recommendations for Cryptococcal ... Recommendations for Cryptococcal ... Recommendations for Cryptococcal ... management #meningitis #cryptococcus
Important Fungal Stains
Mycology Lab:
 • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
polysaccharide capsule of Cryptococcus ... detection for cryptococcal ... mucopolysaccharide capsule of Cryptococcus ... cell walls of Cyptococcus ... fungus #comparison #table
Fungal Pneumonias - Diagnosis Comparison Table
 • Aspergillus
 • Blastomyces
 • Candida
 • Coccidioides
 • Cryptococcus
Diagnosis Comparison Table ... Coccidioides • Cryptococcus ... Diagnosis #Comparison #Table
Rare Invasive Yeasts - Species and Antifungal Therapy

Cryptococcus, 
Geotrichum, 
Kodamaea, 
(Pichia)ohmeri, 
Malassezia, 
Pseudozyma, 
Rhodotorula, 
Saccharomyces, 
Saprochaete
Antifungal Therapy Cryptococcus ... Therapy #Management #Table
Spectrum of activity for systemic antifungal agents
Antifungals: 5FC, flucytosine; AMB, amphotericin B; ANI, anidulafungin; CAS, caspofungin;
Aspergillus fumigatus, Cryptococcus ... antibiogram #management #pharmacology
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview

Mechanism: binds ergosterol in membrane and
: Zygomycetes, Cryptococcal ... #Pharmacology #Antibiotics
Common Fungal Pathology 
 • Candida - Small yeast intermingled with pseudohyphae
 • Aspergillosis - Septate
broad based bud • Cryptococcus ... clinical #microscopy #table
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
infections: Severe cryptococcal ... #Pharmacology #Antibiotics
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
lack activity vs Cryptococcus ... Anidulafungin #Pharmacology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
#management #algorithm ... #pharmacology # ... #medications #table