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diagnosis differential rheumatology management oncology dermatology bruising erythematosus leukemia lupus sle treatment algorithm allergy alopecia anemia aplastic atopic atopy autoimmune
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Sequestration Disordered ... Disease Vascular System ... Connective Tissue Disorders ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... , or other causes ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... , leading to the ... • They can cause ... - Purpura - Skin ... Cryoglobulins Cause
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... Rare Disorder: ... Musculoskeletal system ... Causes: - Idiopathic ... , breast CA - Hematologic
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Demyelinating Syndrome ... , Seizure disorders ... autoantibodies that will cause ... inflammation, leading
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Paradoxical spontaneous bleeding ... processes: • Systemic ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
• Presence of systemic ... and skin haemorrhage ... Marfan syndrome, ... #Bleeding #Disorders ... pediatrics #diagnosis #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Disorders of ... of a platelet disorder ... von Willebrand syndrome ... discern these causes ... Differential #Diagnosis #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... caused by blood ... unusual bruising or bleeding ... just beneath the skin ... #diagnosis #hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
into a 4-pass system ... Eosinophilic GI Disorders ... cell activation syndrome ... Mastocytosis • Other hematologic ... Differential #Diagnosis #hematology
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