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diagnosis management dermatology rheumatology differential algorithm hepatology oncology disease neurology classification eosinophilia cryoglobulinemia dermatitis eosinophils erythematosus gastroenterology hepatopulmonary hes hypereosinophilia
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
• Clinically ... suspect underlying hematologic ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... , or other causes ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm HYPOPIGMENTATION Diffuse Congenital - Generalized hypopigmentation of
Disorders of Pigmentations ... of hair, eyes, skin ... McCune Albright syndrome ... #skin #dermatology ... Diagnosis #Algorithm #causes
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Conjugation == Gilbert Syndrome ... hyperbilirubinemia syndrome ... as jaundice on clinical ... and stress may cause ... Congenital #bilirubin #hepatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cryoglobulins Cause ... : • Clinical triad ... reticularis & skin
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... for secondary causes ... glucocorticoid treatment ... symptoms (eg, skin ... Differential #diagnosis #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... Causes: - Idiopathic ... , breast CA - Hematologic ... Treatment: - Systemic ... #diagnosis #dermatology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
inherited bleeding disorder ... Clinical • ... bruising • Skin ... factor VIII) Treatment ... Disease #Diagnosis #Hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Autoinflammatory disorder ... Rheumatic pain Clinical ... Rule out other causes ... and lower jaw Treatment
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... organ damage • Treatment ... intracellular contents ... Low calcium • Treatment ... diagnosis #management #hematology
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