9 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... 8.0 mg/dL • Potassium ... other symptomatic hypocalcemia ... treatment • Hypocalcemia ... #management #oncology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Normal Acid-Base: Low ... Carbenoxolone, SAME, Cushing ... @priti899 #Hypokalemia ... Algorithm #causes #potassium
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... the basis of the potassium-to-creatinine ... ↓ Aldosterone: Cushing ... #hypokalemia ... #urine #potassium
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... , Elevated Cr, Low ... hydration - Hyperkalemia ... #TLS #diagnosis ... #management #hematology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... previously stable values ... disorders including hypokalemia ... renal bruit or signs ... hormonal excess or hypokalaemia
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... alkalosis • Normal or low ... pressure Labs: • Hypokalemia ... pathophysiology #Hypokalemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... HIV, Influenza, TSS ... Hyperphosphatemia • Hypocalcemia ... /Late - Hypercalcemia ... Monitor potassium
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
and Management ... Acidosis, Cell Lysis (TLS ... reabsorption) Workup ... acidosis) • Low ... #Treatment #potassium
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
and ulcers • Vagus ... • Boerhaave syndrome ... hormonal imbalances (low ... ) • Overall: hypokalemia ... pathophysiology #diagnosis #signs