573 results
Cushing's Reflex - Pathophysiology
HYPERTENSION with a reflex BRADYCARDIA
 → ↑ ICP 
 → ↓ CBF
 →
Cushing's Reflex ... Pathophysiology HYPERTENSION ... response → ↓ HR #Cushings
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework

Hypertension:
 • Hypertensive emergency
 • Hypertensive encephalopathy
Hypertension and ... Diagnosis Framework Hypertension ... : • Hypertensive ... emergency • Hypertensive ... Endocrinopathies: • Cushing
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Secondary Causes of Hypertension ... Diagnosis Algorithm Hypertension ... 130/80 for DM) Hypertensive ... • NO FHx • Hypertensive ... • Steroids (Cushing's
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Primary (Essential) (95%) - Onset between age
Secondary Causes of Hypertension ... Hypertensive urgency ... Resistant hypertension ... Glucocorticoid excess (Cushing ... ) #Hypertension
Cushing Syndrome Testing Algorithm
INDICATIONS FOR TESTING:
 • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension)
Testing:
Cushing Syndrome ... : • Suspected Cushing ... weakness, refractory hypertension ... ARUPConsult @ARUPLabs #Cushing
Evaluation of Secondary Hypertension
 • Primary aldosteronism - PRA, PAC
 • Renal artery stenosis - Renal
Evaluation of Secondary Hypertension ... - TSH, fT4 • Cushing ... PAC #Secondary #Hypertension
Clinical Effects of Large and Small Pituitary Tumours
Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
ring size • Cushing's ... Bruising, Myopathy, Hypertension ... Lethargy, Postural hypotension
Secondary causes of Hypertension
 • Medications, Drugs, Chemo: NSAIDS, Steroids, CNI, Alcohol, Cocaine, OCP, Licorice, MAOI,
Secondary causes of Hypertension ... renin HTN causes: Cushing's ... Secondary #causes #Hypertension
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary Hypertension ... : Resistant hypertension ... persistence of hypertension ... Stage 2 hypertension ... Hypercalcemia, Cushing's
Adrenal Incidentalomas: Hormone Evaluation
 • Zona Glomerulosa: Primary Hyperaldosteronism?
    - Aldosterone and renin
hypokalemia and/or hypertension ... Zona Fasciculata: Cushing