14 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... Rare (SSA+ for cutaneous ... constitutional symptoms ... • Treatment: ... #sle #comparison
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... involvement 3% SLE-Related ... , Cutaneous mimickers ... Lupusreference #SLE ... autoantibodies #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... response -> Subacute cutaneous ... lupus: scaly annular ... #SLE #Mucocutaneous ... diagnosis #signs #symptoms
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
Symptoms Distinguishing ... Groups of Cutaneous ... to hours into treatment ... Onset days into treatment ... dermatology #clinical #comparison
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: • Acute cutaneous ... scarring • Subacute cutaneous ... inflammation Cutaneous ... : • Symptoms limited
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... Treatment of Membranous ... Lupus Nephritis ... treat non-renal SLE ... treat extra-renal SLE
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Differential Diagnosis Algorithm ... Polyarthritis • Systemic Lupus ... with Systemic Lupus ... Erythematosus (SLE ... should have other symptoms
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
any time during treatment ... GBS), systemic lupus ... erythematosus (SLE ... after DC Statin Treatment ... diagnosis #management #treatment
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms ... is rare in DIL, SCLE-DIL ... Rare (SSA+ for cutaneous ... constitutional symptoms ... • Treatment:
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
vasculitis) • Cutaneous ... meningitis), MCC CNS symptoms ... Oral aphthae : SLE ... • Arthritis: SLE ... Arthritis, AS Treatment