9 results
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... result in permanent neurologic ... deficiency - Syrinx ... Lower motor neuron symptoms ... Upper motor neuron symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Loss of parental copy ... Signs/Symptoms ... , sleep apnea, cor ... pulmonale #PraderWilli ... #Syndrome #genetics
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... Framework Spinal cord ... level of spinal cord ... of the spinal cord ... MCTD, Sjogren syndrome
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
meninges in spinal cord ... nerve roots Spinal Cord ... Reconstitution Inflammatory Syndrome ... lymphadenopathy, pulmonary ... Children with pulmonary
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... ‘red flag’ symptoms ... Diagnosis: • Spinal cord ... spondylitis • Tethered cord ... diagnosis #causes #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
disorder (Cardiac, pulmonary ... • Acute stroke syndromes ... of the spinal cord ... Malignancy-associated myositis • Genetic ... Differential #Diagnosis #neurology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogen is a cold ... - Albumin - Cold ... Cryofibrinogenemia Symptoms ... may include: • Cold ... Antiphospholipid syndrome
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
Recurrent Falls Core ... cardiogenic) - Pulmonary ... presyncope, exertional symptoms ... ) - Spinal cord ... Evaluation #Geriatrics #Neurology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
TLS (tumor-lysis syndrome ... replacement Cord ... “big & sticky” cells ... Hyperviscosity syndrome ... renal failure, pulmonary