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diagnosis differential management oncology hemolytic causes classification hemeonc leukemia signs workup aiha algorithm atlas autoimmune chronic cll cold disorders hemolysis
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
AIHA (48-70%) Cold ... HA (paroxysmal cold ... hemoglobinuria) • Cold ... Agglutinin Disease ... Diagnosis #Table #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... of anemia include ... • hemolytic anemia ... sensitize red blood cells ... #hematology #diagnosis
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... anemia (sometimes ... Cell Agglutinate: Cold ... , Paroxysmal cold ... differential #diagnosis #hematology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Tamponade Pulmonary ... - Asthma - COPD ... Transverse myelitis • Hematology ... : - Anemia • ... diagnosis #causes #pulmonary
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
Cold Urticaria Prevalence ... skin contact with cold ... minutes after the cold ... 10.1111/all.14674 #Cold ... Urticaria #diagnosis #rheumatology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Liver diseases ... - Renal diseases ... , Liver diseases ... PD deficiency, Pulmonary ... #differential #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle cells ... Agglutination - Cold ... ARUPLabs #Hemolytic #Anemia ... Algorithm #workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... Autoimmune (AIHA)"Cold ... (e.g. primary cold ... differential #diagnosis #hematology ... #anemia
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
for Hemolytic Anemia ... Causes: • Liver disease ... • AIHA: warm, cold ... #Hemolytic #Anemia ... classification #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogen is a cold ... - Albumin - Cold ... may include: • Cold ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
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