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diagnosis differential management sclerosis signs syndrome algorithm als amyotrophic anorexianervosa bronchiectasis cauda caudaequina causes cryofibrinogenemia disorders equina evaluation falls genetics
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
of the spinal cord ... monophasic Pathophysiology ... to the spinal cord ... Bilateral signs and/or symptoms ... diagnosis #management #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... Framework Spinal cord ... level of spinal cord ... of the spinal cord ... - Transverse myelitis
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Loss of parental copy ... Syndrome Signs/Symptoms ... /Complications: ... , sleep apnea, cor ... pulmonale #PraderWilli
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
meninges in spinal cord ... nerve roots Spinal Cord ... lesion Pott's Disease ... lymphadenopathy, pulmonary ... • Usually is a complication
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... Connective tissue diseases ... obstruction • COPD ... Physical stigmata of cor ... disease Complications
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogen is a cold ... - Albumin - Cold ... Cryofibrinogenemia Symptoms ... may include: • Cold ... thrombophlebitis, pulmonary
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
‘red flag’ symptoms ... Diagnosis: • Spinal cord ... • Transverse myelitis ... spondylitis • Tethered cord ... diagnosis #causes #neurology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... neuritis • Partial myelitis ... Progressive MS (Spinal cord ... objective evidence of neurologic ... diagnosis #management #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Presentation: - Disease ... multiple spinal cord ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... Complications ... or the spinal cord ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms
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