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diagnosis differential management spinalcord syndromes pathophysiology rheumatology sclerosis signs acute algorithm als amyotrophic behcet cancer cauda caudaequina causes cryofibrinogenemia disease
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
cord - Spinal Cord ... Syndromes Spinal ... result in permanent neurologic ... If the spinal cord ... #Cord #syndromes
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... findings • Anterior Cord ... complete • Central Cord ... Syndrome ->Cord ... • Posterior Cord
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... cord neurological ... cord compression ... Cord Causes: 1 ... MCTD, Sjogren syndrome
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
cord and nerve ... roots Spinal Cord ... Reconstitution Inflammatory Syndrome ... lymphadenopathy, pulmonary ... Children with pulmonary
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Hyperviscosity Syndrome ... of breath • Neurologic ... neutrophil count < 500 cells ... Malignant Epidural Spinal ... Cord Compression
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
L1-L5 Symptoms ... ‘red flag’ symptoms ... cord infarct ... spondylitis • Tethered cord ... diagnosis #causes #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
cord resulting ... cord that results ... cord (Myelopathy ... Bilateral signs and/or symptoms ... diagnosis #management #neurology
Incomplete spinal cord syndromes (ISCS) • Central - Small Lesion - Suspended sensory deficit, classic cape
Incomplete spinal ... cord syndromes ... lesion of cervical cord ... (anterior horn cells ... #diagnosis #neurology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
: inheriting 2 copies ... Loss of parental copy ... Signs/Symptoms ... , sleep apnea, cor ... pulmonale #PraderWilli
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
disorder (Cardiac, pulmonary ... • Acute stroke syndromes ... Lesions of the spinal ... cord • Inflammatory ... Differential #Diagnosis #neurology
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