892 results
Janeway Lesions in Endocarditis seen on Physical Exam 

Dr Supradip Ghosh
@dr_supradip

36 year old male with history
left hemiplegia, fevers ... sister shared these photos ... with persistent fever ... - Clinical examination ... #photo #dermatology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
alter inflammatory cytokine ... GCA is almost never ... /Symptoms: - Fever
Faget's Sign & Liebermeister's Rule
Pulse-Temperature Dissociation
EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM
INFECTIOUS
Psittacosis • Q Fever ... • Typhoid Fever ... • Drug Fever ... CLINICAL UTILITY ... Typhoid Fever (S
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
pro-inflammatory cytokines ... hemophagocytosis and cytokine ... syndromes Clinical ... is the main clinical ... - Nonremitting fever
Acute Schistosomiasis: Katayama Fever
 • Most common in travelers and children
 • "Swimmers Itch" in the
Schistosomiasis: Katayama Fever ... exposure) • Fever ... Schistosomiasis #Katayama #Fever ... #diagnosis #clinical ... #photo
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
Pathogenesis of Rheumatic Fever ... Pathogenesis of rheumatic fever ... infiltration leading to cytokine-mediated ... #Rheumatic #Fever
Scarlet fever
• Delayed-type skin reactivity to pyrogenic exotoxin Requires prior exposure
• Diffuse erythematous eruption that generally
Scarlet fever • ... folds #Scarlet #fever ... #diagnosis #clinical ... #photo #signs #
Ever had a #traveler come in to your clinic with #fever and you were not sure
Ever had a #traveler ... come in to your clinic ... with #fever and ... infectiousdisease #fever
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Fever vs Hyperthermia ... Fever: • Regulated ... Endotoxins, Toxins, Cytokines ... BrighamChiefs #Fever
Cutaneous Manifestations of Monoclonal Gammopathy
 • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Xanthomatosis • Cytokine ... dermatology #skin #clinical