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Causes of Fever: IMADE Mnemonic INFECTION • Infection 1.0 - Common & Localizing: Base Rate • Infection
Causes of Fever: ... carcinomas present with fever ... increased inflammtory cytockines ... with DVT/PE + fever ... IMADDE #diagnosis #differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Pathophysiology: • Cytokine ... Subacute-Acute: • Common: fever ... initiation • Differential
Ever had a #traveler come in to your clinic with #fever and you were not sure
your clinic with #fever ... to narrow your differential ... to narrow your differentials ... #differentials # ... infectiousdisease #fever
Faget Sign - Pulse-Temperature Dissociation Causes of Relative Bradycardia • Infectious Causes: Legionella, Psittacosis, Q fever, Typhoid
Psittacosis, Q fever ... , Typhoid fever, ... , Dengue fever, ... , Drug fever ... #bradycardia #differential
Hypothermia in Sepsis - Pathophysiology • 20% of septic pts → HYPOTHERMIA • Increased mortality 62%
proinflammatory cytokines ... anti-inflammatory cytokine
Causes of Relative Bradycardia - Note the propensity for intracellular organisms. Infectious: Legionella, Psittacosis, Q fever, Typhoid
Psittacosis, Q fever ... , Typhoid fever, ... , Dengue fever, ... , Drug fever ... bradycardia #Causes #differential
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
alter inflammatory cytokine ... GCA is almost never ... /Symptoms: - Fever
Faget's Sign & Liebermeister's Rule Pulse-Temperature Dissociation EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM INFECTIOUS
• Typhoid Fever ... • Drug Fever ... Typhoid Fever (S ... help hone your differential ... Dissociation #diagnosis #differential
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - ... Differential Diagnosis ... Continuous Fever ... (Step ladder: fever ... #Patterns #Differential
Differential Diagnosis of Fever and Splenomegaly - Typhoid - Infective endocarditis - Miliary tuberculosis - Hodgkin
Differential Diagnosis ... of Fever and Splenomegaly ... Brucellosis #Fever ... #Splenomegaly #Differential
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