15 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
of Abnormal Coagulation ... and Prolonged PT ... #Coagulation #Abnormal ... #Hematology #Diagnosis ... #Workup
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
, Normal PT (INR ... , Normal PT (INR ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology #coagulation
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Algorithm • 12 ... -13 g/dL, • ANC ... iron studies, PT ... /aPTT Differential ... #Algorithm #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... #PT #aPTT #Prolonged ... #Causes #diagnosis ... #differential #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management Algorithm ... /aPTT normal • ... #Differential #Diagnosis ... #hematology
Chest Pain - Diagnosis and Workup Algorithm

History and Exam
Acute life-threatening causes:
 • Acute myocardial infarction
 •
Chest Pain - Diagnosis ... and Workup Algorithm ... , LET, lipase, PT ... . aPTT • Serial ... #Algorithm #workup
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
platelet aggregation PT ... , aPTT: • Expected ... using INR use PT ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... Fibrinogen: ↓ • PT ... INR < 2.3 - APTT ... #diagnosis #causes ... treatment #management #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
PT and the aPTT ... amyloidosis #Abnormal ... #PT #aPTT #Prolonged ... #differential #hematology ... #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... #Hematology