45 results
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
//www.nejm.org/doi ... ejection fraction, treatment ... cardiovascular causes ... , aborted cardiac ... dCHF #Cardiology #EBM
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... and Differential Diagnosis ... osmolarity If cause ... investigations depending on clinical ... ANCA, ANA, Anti-GBM
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Differential Diagnosis ... Identification of onset (acute ... symptoms (HA, nausea ... Medical history (cardiac ... #EM #IM #Nephro
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... fever - ACS, AKI ... , acute limb ischemia ... with tetany or cardiac ... Syndrome #TLS #diagnosis
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
Cardiac Tamponade ... help and inform clinical ... • Diagnostic ... thoracotomy is a better treatment ... #Tamponade #Anesthesiology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
GrepMed Handbook Clinical ... on ABx) → Acute ... Diarrhea (>3 BM ... Treatment Guideline ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... Treatment: • ... #management #treatment
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Differential Diaqnoses ... Coxsackie, CMV, EBV ... , DIC, TMA • Cardiac ... #management #treatment
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
trolley, anaphylaxis treatment ... require prolonged treatment ... an appropriate critical ... #Anaphylaxis #Anesthesiology ... Intraoperative #Checklist #Diagnosis
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Renal: (AKI ... antibody, Anti-GBM ... (UPC) ratio • Cardiac ... Goodpasture's cause ... #management #treatment