32 results
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
//www.nejm.org/doi ... ejection fraction, treatment ... cardiovascular causes ... , aborted cardiac ... dCHF #Cardiology #EBM
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
osmolarity If cause ... investigations depending on clinical ... ANCA, ANA, Anti-GBM ... syndrome: troponin ... CK-MB, NT-proBNP, cardiac
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... Calcium ≤ 7.0 mg/dL Clinical ... TLS: • AKI (defined ... age and sex) • Cardiac ... #TumorLysis #Syndrome
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... fever - ACS, AKI ... organ damage • Treatment ... lethargy, hematuria, cardiac ... with tetany or cardiac
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Treatment depends ... maintained fever CAUSES ... #Differential #Causes ... #Anesthesiology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
changes and may cause ... severe clinical ... thiamine) Late: • Cardiac ... • Delirium DDX ... hyperparathyroidism Treatment
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
Cardiac Tamponade ... help and inform clinical ... • Call for cardiac ... thoracotomy is a better treatment ... #Tamponade #Anesthesiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... Dermatomyositis Clinical ... declines > ALT) • AKI ... + myoglobin AKI ... Treatment of underlying
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
• Unexpected cardiac ... trolley, anaphylaxis treatment ... require prolonged treatment ... an appropriate critical ... #Anaphylaxis #Anesthesiology
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
be divided into cardiac ... carotid sinus syndrome ... should be guided by clinical ... The treatment strategy ... depends on the cause