28 results
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
//www.nejm.org/doi ... ejection fraction, treatment ... cardiovascular causes ... , aborted cardiac ... dCHF #Cardiology #EBM
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
osmolarity If cause ... investigations depending on clinical ... ANCA, ANA, Anti-GBM ... syndrome: troponin ... CK-MB, NT-proBNP, cardiac
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... Calcium ≤ 7.0 mg/dL Clinical ... TLS: • AKI (defined ... age and sex) • Cardiac ... #TumorLysis #Syndrome
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... fever - ACS, AKI ... organ damage • Treatment ... lethargy, hematuria, cardiac ... with tetany or cardiac
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
changes and may cause ... severe clinical ... thiamine) Late: • Cardiac ... • Delirium DDX ... hyperparathyroidism Treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... Dermatomyositis Clinical ... declines > ALT) • AKI ... + myoglobin AKI ... Treatment of underlying
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
be divided into cardiac ... carotid sinus syndrome ... should be guided by clinical ... The treatment strategy ... depends on the cause
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Renal: (AKI ... nose deformity • Cardiac ... (UPC) ratio • Cardiac ... Goodpasture's cause ... diagnosis #management #treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... and petechiae Causes ... and thymoma DDX ... aplastic anemia Treatment
This is a quick overview of hormonal acne treatment for the medical student and resident.

Keep in
hormonal acne treatment ... #dermatology #treatment ... Trivedi M, Clark AK ... Koo EB, Petersen ... data review of 70 cases