12 results
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
//www.nejm.org/doi ... ejection fraction, treatment ... spironolactone did ... causes, aborted cardiac ... dCHF #Cardiology #EBM
Fremanezumab for the Preventive Treatment of Chronic Migraine - Primary and Secondary End Points #EBM #Neuro
the Preventive Treatment ... Secondary End Points #EBM ... #Neuro #IM #Fremanezumab ... #Migraine #CGRP
Fremanezumab for the Preventive Treatment of Chronic Migraine - Primary and Secondary End Points #EBM #Neuro
the Preventive Treatment ... Secondary End Points #EBM ... #Neuro #IM #Fremanezumab ... #Migraine #CGRP
Fremanezumab for the Preventive Treatment of Chronic Migraine - Adverse Events in the Safety Population, According
the Preventive Treatment ... to Trial Group #EBM ... #Neuro #IM #Fremanezumab ... #Migraine #CGRP
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Coxsackie, CMV, EBV ... , DIC, TMA • Cardiac ... diagnosis #management #treatment ... #rheumatology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
nose deformity • Cardiac ... antibody, Anti-GBM ... (UPC) ratio • Cardiac ... EGPA • ESR and CRP ... diagnosis #management #treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Toxic injury to BM ... Parvovirus B19 - EBV ... and thymoma DDX ... aplastic anemia Treatment ... Anemia #oncology #hematology
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
recommendations, treatments ... #medications #treatment ... Petersen EBM, Skov ... EL, Richardson IM ... (5):1821-1829. doi
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
dental procedure • Cardiac ... : • New cardiac ... Glomerulonephritis DDX ... Criteria • ↑ ESR, CRP ... hematuria, + RF Treatment
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
hypertension and/or drug treatment ... replacing the BM ... replacing the BM-common ... cell aplasia DOI ... diagnosis #causes #hematology