544 results
Statin Drug-Drug Interactions with HIV ART Medications
PIs - NNRTIs - ISTIs
Dose Adjustments

doi: 10.20945/2359-3997000000306

#Statin #Drug #Interactions #DDIs
Dose Adjustments doi ... #Interactions #DDIs
Amiodarone Toxicity and Monitoring

Tremor Ataxia 
Ocular neuritis 
Corneal Microdeposits 
Bradycardia 
Pulmonary fibrosis 
Hepatotoxicity 
Blue-gray skin
P-Glycoprotein - Key DDI
Cannon A Waves on Neck Examination

Cannon a waves! Notice that it occurs randomly, not predictably w/
dual-chamber PPM set for DDI
Paxlovid Drug-Drug Interactions
Before prescribing ritonavir-boosted nirmatrelvir (Paxlovid) for outpatient treatment of COVID-19, determine whether the patient
#Interactions #DDI
Rate of Correction of Hypernatremia and Health Outcomes in Critically Ill Patients

CJASN May 2019, 14 (5)
14 (5) 656-663; DOI ... Conclusions We did ... EBM #Nephrology #VisualAbstract
Central vs Nephrogenic Diabetes Insipidus - Desmopressin Challenge
Give desmopressin (intranasal, SQ, IV) and monitor UOsm every
300 - Complete NDI ... 300 - Partial NDI ... 300 - Partial CDI ... 100% - Complete CDI ... Diabetes #Insipidus #DI
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
//www.nejm.org/doi ... spironolactone did ... Cardiology #EBM #VisualAbstract
POLAR Randomized Clinical Trial - Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients
21):2211-2220. doi ... with normothermia did ... CriticalCare #ICU #VisualAbstract
Rate of Correction of Hypernatremia and Health Outcomes in Critically Ill Patients

CJASN May 2019, 14 (5)
14 (5) 656-663; DOI ... Conclusions: We did ... Management #EBM #VisualAbstract
NICE-SUGAR - Intensive versus Conventional Glucose Control in Critically Ill Patients
N Engl J Med 2009; 360:1283-1297
//www.nejm.org/doi ... mortality than did ... Endocrinology #VisualAbstract