13 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... -> AML: Blast crises ... pain, bleeding, infections ... bruising, bleeding, infection ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... Lymphocytosis: Absolute blood ... lymphocyte > 5000/microL ... leukemia #CLL ... workup #oncology #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Diagnosis Algorithm Infectious ... • Lymphoma • Leukemia ... Serum Sickness Hemolytic ... Disease • Sickle Cell ... #Hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... Diabetes/DKA Infections ... : • helminth infections ... Chickenpox Other Causes ... #hematology #basophils
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis): • Acute infection ... iron deficiency, hemolysis ... Chronic myeloid leukemia ... (CML) - Dr. ... #hematology #secondary
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Causes purpura & ... Infection - Infection ... infections with ... diagnosis #management #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Causes: - Idiopathic ... , breast CA - Hematologic ... neutrophils in the blood
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... Chronic Myelogenous Leukemia ... Leukemia • Idiopathic ... • Parvovirus infection ... Syndromes #diagnosis #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
maculopapular rash ... Causes purpura & ... • Infection - ... Infection occurs ... diagnosis #management #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... disease • Infectious ... and autoimmune hemolytic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology