1067 results
Drug-Induced Liver Injury - Pathophysiology
Indirect
Idiosyncratic
Direct

BWH Medicine Chiefs @BrighamChiefs

#DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Liver Injury - Pathophysiology ... BrighamChiefs #DILI ... Liver #Injury #Pathophysiology
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... Pharmacology #Causes #DILI
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Liver Injury (DILI ... ) DILI Types: ... disease 6-9 mo after DILI ... • Cholestatic DILI ... EmoryGastroHep #DILI
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
- Positive: CD2 ... , CD3, CD8 - Loss ... of CD5 and/or CD7 ... Rarely can be CD4
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Liver Injury (DILI ... Diagnosis Algorithm DILI ... injury, Previous DILI ... hepatitis #DILI
Autoimmune Gastritis - Pathophysiology

Anti-ParietaI Cell, CD4+ T Cells, Autoantibodies -> x Parietal Cells, x HCL, x
Autoimmune Gastritis - Pathophysiology ... Anti-ParietaI Cell, CD4 ... Autoimmune #Gastritis #Pathophysiology
HFNC compared to NIV
HFNC:
- Comfort - Higher comfort  Eating, drinking and speaking less impaired 
-
preload - P-SILI ... /VILI - Lower risk
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- T-cell - CD7 ... , CD3 Chronic ... - B-cell CD5
Amiodarone-Induced Lung Iniurv (AILI) - Timeline
Hours to days (peri-procedurally): ARDS
Days to months: DAH
Weeks: Eosinophilic pneumonia
Weeks to
Amiodarone-Induced Lung Iniurv (AILI ... Induced #LungIniurv #AILI
Sexually Transmitted Diseases: Summary of 2015 CDC Treatment Guidelines
These summary guidelines reflect the 2015 CDC Guidelines
Summary of 2015 CDC ... reflect the 2015 CDC ... SexuallyTransmittedDiseases #CDC