12 results
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Blockers: • MOA ... inotropy) ACCP Cardiology ... Vaughan #Williams #Pharmacology ... #pathophysiology ... #cardiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... inotropy) ACCP Cardiology ... Antiarrhythmics #Pharmacology ... #pathophysiology ... #phases #cardiology
Cardiac Valve Replacement - Anticoagulation INR Targets and Antiplatelet by Valve Type

Bioprosthetic valves require at least
Replacement - Anticoagulation ... months (up to 6 mo ... K antagonist (VKA ... VKA can be stopped ... #Management #Cardiology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... #management #algorithm ... #pharmacology # ... #decisionaid #cardiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... C-ANCA): GPA >>> MPA ... P-ANCA): eGPA, MPA ... differential #diagnosis #algorithm
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... intracellular calcium causes ... #Pathophysiology ... #cardiology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
• Green tea, Ma-huang ... vera, Licorice - Causes ... potential arrhythmias Class ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... ARB/ACE-I/ARNI/MRA ... suggest prophylactic anticoagulation ... diagnosis #management #cardiology
Anticoagulant Therapy after PCI (patients with AFib)
Dual-Therapy Preferred:
 • Triple therapy = increased bleeding
use of DOAC (vs VKA ... derick_gabel via ACCP Cardiology ... Triple #therapy #anticoagulation ... #PCI #pharmacology ... #management #cardiology
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
ASA class If ... event, follow ACC algorithm ... Anticoagulation ... one post op Cardiology