11 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Clotmaster #VTE #DOAC ... #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban ... #Pharmacology #Hematology
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
Anti-Coagulants • Rivaroxaban ... • Apixaban ... • Dabigatran ... #Prescribing #hematology ... #management #Direct
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
- Atrial Fibrillation ... AFib: CrCl 15-50 ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology ... #Apixaban #Rivaroxaban
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Management Cheat ... Sheet: Warfarin, Apixaban ... , Dabigatran, Rivaroxaban ... Anticoagulant #DOAC
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Pathophysiology Anticoagulation ... warfarin) for chronic anticoagulation ... accelerates the bridging ... Heparins #LMWH #UFH #DOAC ... #Dabigatran #Apixaban
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
Antidotes: • Apixaban ... , Edoxaban or Rivaroxaban ... modified factor Xa • Dabigatran ... #Oral #anticoagulant ... #hematology #management
Anticoagulation for Atrial Fibrillation - CHA2DS2-VASc

I always tell my students, one of the first thing you
for Atrial Fibrillation ... guidelines recommend DOAC ... AtrialFibrillation #AFib ... #CHADSVASC #CHADS2VASC ... #Score #Management
Atrial Fibrillation (A-Fib) Summary

Symptoms:
• Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

Why?
Cardiac:
	• Valvular heart
Atrial Fibrillation ... typically needed • DOACs ... Xa inhibitors (rivaroxaban ... , apixaban, edoxaban ... #management #cardiology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
, edoxaban and rivaroxaban ... direct-acting oral ... randomized controlled trial ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... direct acting oral ... of Therapy • Dabigatran ... inhibitor) • Apixaban ... , Edoxaban, Rivaroxaban