7 results
Muddy Brown Granular Casts three ways - Brightfield, Darkfield, Phase Contrast.

Dr. Vipin Varghese @vipvargh

#Muddy #Brown #Granular
Muddy Brown Granular ... #Granular #Casts ... #clinical #urine ... #microscopy #MBGC ... #nephrology
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
and concentrated urine ... "Muddy-brown" heme-granular ... casts are seen ... tubulointerstitial nephritis, renal ... #Differential #Microscopy
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... also be seen if urine ... disease • Granular ... • “Muddy brown ... key #diagnosis #nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... • "Muddy Brown ... ) • Granular Casts ... #Urine #Microscopy ... #nephrology #interpretation
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
• 1ml blood/liter ... hematuria: - RBC casts ... Dysmorphic RBC - Brown ... #nephrology #renal ... #urine #blood
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- Urinalysis/microscopy ... UOP/weights - Urine ... ATN - 45% - Pre-renal ... mostly ATN and pre-renal ... #Nephrology #Diagnosis
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
(no casts, protein ... , or blood) ... Normal kidney ultrasound ... essential in all cases ... Syndrome #Hepatology #Nephrology