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diagnosis nephrology differential algorithm clinical neurology management nephritic physicalexam acute aki glomerulonephritis gunn hematuria injury jaw marcus microscopy phenomenon proteinuria
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... but in severe cases ... #Nephrotic #Syndromes
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
/nephritic syndromes ... the patient have glomerular ... hematuria (RBC casts ... dysmorphic RBCs in urine ... #Algorithm #Nephrology
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome == Nephrotic Syndrome == Onset - Insidious Edema - ++++ Blood
Syndrome and Nephritic ... Syndrome == Nephrotic ... Red blood cell casts ... Red blood cell casts ... #Syndrome #Nephritic
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... • Evidence of glomerular ... proteinuria, RBC casts ... if cause not identified ... Diagnosis #Algorithm #Workup
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
• White cell casts ... infection • Hyaline casts ... disease • Granular casts ... key #diagnosis #nephrology ... #casts
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... and concentrated urine ... breakdown of cellular casts ... heme-granular casts ... 34t5DgJ #Urinary #Casts
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... pain hematuria syndrome ... hematuria: - RBC casts ... • Nutcracker syndrome ... #urology #nephrology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic ... sydnrome • Pigment ... non-infectious) - Dr ... #nephrology #interpretation
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... osmolarity If cause ... • Interstitial nephritis ... #Injury #AKI #Workup ... #causes
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
hemolytic-uremic syndrome ... cell/white cell casts ... urine sediment ... Nephrocalcinosis causes ... #syndrome #nephrology
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