21 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... for alternative causes ... HBV, HCV, HEV, EBV ... hepatitis #DILI #DrugInduced
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... Treatment: • ... #management #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... Lupusreference #druginduced ... #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Mechanisms: • Direct Damage ... Aplastic Anemia Clinical ... and petechiae Causes ... aplastic anemia Treatment ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Fibrinolysis → End organ damage ... Clinical Findings ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
auscultation, JVD ... & Dry) is the treatment ... the determined cause ... & Dry” is the treatment ... heartfailure #chf #criticalcare
A quick infographic on the importance of sun protection and the various results of sun damage
#wavelengths #causes ... #diagnosis #dermatology ... non-melanoma skin cancer: clinical ... Arch Dis Child. ... Mechanisms and treatments
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
recommendations, treatments ... #diagnosis #causes ... Petersen EBM, Skov ... Arch Dis Child. ... (5):1821-1829. doi
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential Diagnosis ... hypertension and/or drug treatment ... cell aplasia DOI ... #differential #diagnosis ... #causes #hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vessels involved/damaged ... Diagnosis = clinical ... identifies 85 to 95% of cases ... of the steroid treatment ... Treatment of GCA