32 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
Acute promyelocytic ... overt cytoplasmic granules ... #Auer #Rods #Acute ... promyelocytic #leukemia #APL ... #Hematology #Clinical
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... diagnosed with acute ... decreased secondary granules ... also described in acute ... Rods #AuerRods #APL
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... (Acute Myeloid ... distinctive primary granules ... #Leukemia #Hematology
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
of crystallized granules ... are typical for acute ... myelogenous leukemia (AML ... Rods #AuerRods #AML
Presentation of malignant disease in children 
Pre-school (<5 years old) 
 - Acute lymphoblastic leukaemia
years old) - Acute ... leukaemia - (ALL ... School-aged - Acute ... Adolescence - Acute ... Malignant #Childhood #Peds
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case of acute ... #neutrophils #AML ... #Clinical #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Presentation: Subacute-Acute ... • Rare: DAH, acute ... , Anaphylaxis, Acute ... unless severe APLS ... diagnosis #management #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
histamine in their granules ... translocation • Acute ... thrombocythemia • Acute ... Diagnosis #causes #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
RED FLAGS - In all ... neurology, back pain Haematology ... cell disease Rheumatology ... Pathway #Child #Peds
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm Acute ... • Myloid (AML ... • Lymphoid (ALL ... Blood #Disorders #hematology